Summaries by Inventor Miyoshi, Hiroyuki

Fibroblast-Derived Cell Line Producing Wnt3a, R-spondin 3, & Noggin
Miyoshi, Hiroyuki ; Stappenbeck, Thaddeus
T-014239

— Tangible Tool: Growth factor over-expressing cell line. Notes: Produces conditioned media to grow various mammalian tissue stem cells.These supportive L-WRN cells can produce conditioned media containing Wnt3a, R-spondin, and Noggin for the the support of gastrointestinal stem cells. This system can be used to make stem cell enriched epithelial spheroids from the mouse gastrointestine. Publication: In vitro expansion and genetic…